Advanced NMR spectroscopy
Technical University of Denmark
General course objectives:
The aim of the course is to give an overview of the 1D and multidimensional NMR techniques that may be used in e.g. NMR based structural and functional analysis. Furthermore, the participants will acquire skills in applying advanced NMR methods to solve analytical problems.
Learning objectives:
A student who has met the objectives of the course will be able to:- Demonstrate knowledge of which structural and functional information may be obtained from the different 1D, 2D and 3D homo- and heteronuclear NMR techniques.
- Perform a theoretical presentation of different NMR experiments.
- Analyze conformational, structural and functional problems within organic and biological compound classes using advanced NMR methods.
- Demonstrate practical experience with acquisition of NMR experiments and knowledge of which parameters are important for the individual experiments.
- Demonstrate theoretical and practical experience with data processing of the individual NMR experiments.
- Present a NMR based structural or functional analysis of an organic compound both written and orally.
- Predict which NMR experiments to use to solve a given structural or functional problem.
- Extract spatial information from complicated 1D NOE and 2D NOESY spectra.
Contents:
The course will cover an introduction to the different 1D, 2D and 3D homo- and heteronuclear NMR techniques with emphasis on what type of structural information the different NMR experiments yield. This will include a theoretical and a practical description of the experiments, data acquisition and data processing routines. The analysis of different conformational, structural and functional problems related to organic and biologically interesting compound classes will be covered.
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Course organizer
Charlotte Held , Sebastian , Kasper
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Place/Venue
Anker Engelunds Vej 1
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City
2800 Kgs. Lyngby
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Country
Denmark
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Workload
5
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Link
http://kurser.dtu.dk/course/26944
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