Metabolism D
Aalto University
<p>The focus is metabolism on a fundamental level relevant to all forms of life, with emphasis on the chemistry of intermediates. Careful look at the balance of atoms, electrons (redox state) and energy during metabolic pathways. </p><p>One part is the aerobic energy metabolism (catabolism): glycolysis, citric acid cycle, electron transport and oxidative phosphorylation, degradation of lipids, amino acids, nucleotides. Selected anabolic pathways ("reverse direction") will be discussed: gluconeogenesis, fatty acid synthesis, amino acid synthesis. </p><p>A second part is the anaerobic metabolism, with a focus on CO2 fixation. Calvin cycle, reverse citric acid cycle, introduction to all known CO2-fixation pathways. Bioenergetics. Energy conservation in methanogens and acetogens. Utilization of hydrogen as an electron source. Concept of electron bifurcation.</p><p>Applications of metabolic pathways for the production of value-added products from CO2 or from biomass-derived feedstocks. Introduction to metabolic engineering. </p>
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Course dates
01 September 2025 - 02 December 2025
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Course organizer
Silvan Scheller
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Place/Venue
School of Chemical Engineering / Department of Bioproducts and Biosystems
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City
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Country
Finland
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Workload
5
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Link
https://mycourses.aalto.fi/course/search.php?...
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